Biostatistics

Our studies are mainly concerned with reference values for spirometric and body plethysmographic parameters. The measurements has been carried out in Austria (data basis: more than 21.000 children and adults from 5 to 90 years) and in Germany (data basis: around 1.900 children from 5 to 18 years). Our reference equations for the Austrian population has been approved as standard values for use in clinical practice. Good links on this subject are:
National Jewish Medical and Research Center, The Thorac Society of Australia and New Zealand. Other topics are breast cancer research and the analysis of dysplasia registers.

Recent papers and diploma theses on this topics are:

• Radaschitz R., Die Anwendung der Scan Statistik auf Daten des Steirischen Fehlbildungsregisters, Diploma thesis in cooperation with the Department of Medical Informatics, Statistics and Documentation, University of Graz (Prof. Andrea Berghold), pp. 76, 2003.
• Genser B., Analyse palliativer Therapiesequenzen beim metastasierten Mammakarzinom unter Anwendung von Multi-State Modellen, Appendix, PhD thesis, pp. 134, 2002.
• Manzke H., E. Stadlober, H.-P. Schellauf (2001), Combined body plethysmographic, spirometric and flow volume reference values for male and female children aged 6 to 16 years obtained from "hospital normals" , European Journal of Pediatrics 160 (2001) 5, 300-306. The original publication is available on LINK http://link.springer.de/link/service/journals/00431/bibs/1160005/11600300.htm
• Manzke H., E. Stadlober, H.-P. Schellauf (2000), Combined body plethysmographic, spirometric and flow volume reference values for male and female children obtained from hospital normals aged 6 to 16 years, Research Report No. 19, Institute of Statistics, University of Technology Graz, 15 pp.
• Manzke H., E. Stadlober, K. Kuehnel, M. Seidel, H.-P. Schellauf (1999), Spirometric, body plethysmographic and flow volume reference values for male and female children aged 5 to 18 years, Research Report No. 16, Institute of Statistics, Technical University Graz, 15 pp.
• Bischof H., Modellierung und Vergleich spirometrischer Parameter von Rauchern und Nichtrauchern, Diploma thesis, pp. 162, 1997.
• Hamberger M., Statistische Analyse dreier Arten von unspezifischen bronchialen Provokationstests an Kindern, Diploma thesis, pp. 339, 1996.
• Manzke H., E. Stadlober, K. Kuehnel, M. Seidel, J. Wehner (1995), New spirometric and plethysmographic reference values in boys and girls aged 4 to 18 years, The European Respiratory Journal 8, Suppl. 19, p. 130s.
• Kummer Ch., Spirometrische Bezugswerte fuer Maedchen und Frauen, Diploma thesis, pp. 83, 1995.
• Rapatz G., Die Modellierung der Lungenfunktionsentwicklung bei Knaben und Maennern, Diploma thesis, pp. 120, 1995.
• Kuehnel K., Referenzmodelle fuer spirometrische und bodyplethysmographische Messparameter von Knaben, Diploma thesis, pp. 190, 1995.
• Seidel M., Spirometrische und bodyplethysmographische Normalwerte von Maedchen, Diploma thesis, pp. 206, 1995.